Investigation of Synbiotic Effect in Thai Night Shift Workers Identified by Epworth Sleepiness Scales

Phuttharaksa Phumcharoen, Wichian Sittiprapaporn

Abstract


Many sleep disorders are characterized by excessive sleepiness. As a type of circadian rhythms sleep-wake disorder, shift work sleep disorder consists of insomnia or excessive drowsiness caused by a recurrent task schedule that crosses with usual sleep hours. Night-shift workers have a disrupted circadian rhythm, indicating less overall sleep time than evening and day workers. Probiotic supplementation has been found to improve subjective sleep quality, associated with balancing gut microbiota. The objective was to investigate the sleeping habits of night shift workers after treating with a synbiotic supplement. Eleven excessive drowsiness among night-shift workers was included in this study. Epworth Sleepiness Scale assessed each participant. For 8 weeks, all participants were given a synbiotic supplement containing 7 probiotics and 3 prebiotics once a day. The Epworth Sleepiness Scales of night shift workers who participated in the pre-intervention showed that most of the night shift workers were mild excessive daytime sleepiness, while fewer night shift workers showed moderate excessive daytime sleepiness. It was found that most of the night shift workers were moved to lower normal daytime sleepiness, while the less of night shift workers showed higher normal daytime sleepiness. It showed a significant improvement of the Epworth Sleepiness Scales (p=0.003). Although these data are preliminary, they may not reflect all of the night shift workers' sleep propensities after treatment with synbiotics. It requires more research to be conducted in a wider scale.

Keywords


Sleep; shift worker; excessive sleepiness; epworth sleepiness scale; synbiotic.

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References


W. Dieterich, M. Schink, and Y. Zopf, “Microbiota in the Gastrointestinal Tract,†Medical sciences (Basel, Switzerland), vol. 6(4), 116, 2018. https://doi.org/10.3390/medsci6040116

B.A. Matenchuk, P.J. Mandhane, and A.L. Kozyrskyj, “Sleep, circadian rhythm, and gut microbiota,†Sleep Med Rev., vol. 53, 101340, 2020. https://doi.org/10.1016/j.smrv.2020.101340.

A.C. Reynolds, J.L. Paterson, S.A. Ferguson, D. Stanley, K.P. Jr Wright, and D. Dawson, “The shift work and health research agenda: Considering changes in gut microbiota as a pathway linking shift work, sleep loss and circadian misalignment, and metabolic disease,†Sleep Med Rev., vol. 34, pp. 3-9, 2017. https://doi.org/10.1016/j.smrv.2016.06.009.

S.L. Chellappa, C.J. Morris, and F.A.J.L. Scheer, “Effects of circadian misalignment on cognition in chronic shift workers,â€. Sci Rep., vol. 9, 699, 2019. https://doi.org/10.1038/s41598-018-36762-w

S. Jehan, F. Zizi, S.R. Pandi-Perumal, A.K. Myers, E. Auguste, G. Jean-Louis, and S.I. McFarlane, “Shift Work and Sleep: Medical Implications and Management. Sleep Med Disord., vol. 1(2), pp. 36-42, 2017. https://doi.org/10.15406/smdij.2017.01.00008

S. Ganesan, M. Magee, J.E. Stone, M.D. Mulhall, A. Collins, M.E. Howard, S.W. Lockley, S.M.W. Rajaratnam, and T.L. Sletten, “The Impact of Shift Work on Sleep, Alertness and Performance in Healthcare Workers. Sci Rep., vol. 9, 4635, 2019. https://doi.org/10.1038/s41598-019-40914-x

J. Ritonja, K.J. Aronson, R.W. Matthews, D.B. Boivin, and T. Kantermann, “Working Time Society consensus statements: Individual differences in shift work tolerance and recommendations for research and practice. Ind Health., vol. 57(2), pp. 201-212, 2019. https://doi.org/10.2486/indhealth.SW-5.

Y. Xie, Q. Tang, G. Chen, M. Xie, S. Yu, J. Zhao, and L. Chen, “New Insights Into the Circadian Rhythm and Its Related Diseases,†Front. Physiol., vol. 10, 682, 2019. https://doi.org/10.3389/fphys.2019.00682

R.W. Logan, and C.A. McClung, “Rhythms of life: circadian disruption and brain disorders across the lifespan,†Nat Rev Neurosci., vol. 20, pp. 49–65, 2019. https://doi.org/10.1038/s41583-018-0088-y

A. Polo, S. Singh, A. Crispo, M. Russo, A. Giudice, M. Montella, G. Colonna, and S. Costantini, “Evaluating the associations between human circadian rhythms and dysregulated genes in liver cancer cells,†Oncol Lett., vol. 14(6), pp. 7353-7359, 2017. https://doi.org/10.3892/ol.2017.7109.

T. Momma, H. Okayama, M. Saitou, H. Sugeno, N. Yoshimoto, Y. Takebayashi, S. Ohki, and S. Takenoshita, “Expression of circadian clock genes in human colorectal adenoma and carcinoma. Oncol Lett., vol. 14(5), pp. 5319-5325, 2017. https://doi.org/10.3892/ol.2017.6876.

J. Zhao, X. Zhou, Q. Tang, R. Yu, S. Yu, Y. Long, C. Cao, J. Han, A. Shi, J.J. Mao, X. Chen, and L. Chen, “BMAL1 Deficiency Contributes to Mandibular Dysplasia by Upregulating MMP3,†Stem Cell Reports, vol. 10(1), pp. 180-195, 2018. https://doi.org/10.1016/j.stemcr.2017.11.017.

A. Angelousi, E. Kassi, N. Nasiri-Ansari, M.O. Weickert, H. Randeva, and G. Kaltsas, “Clock genes alterations and endocrine disorders,†Eur J Clin Invest., vol. 48(6), 12927, 2018. https://doi.org/10.1111/eci.12927.

S. Hergenhan, S. Holtkamp, and C. Scheiermann, “Molecular Interactions Between Components of the Circadian Clock and the Immune System,†J Mol Biol., vol. 432(12), pp. 3700-3713, 2020. https://doi.org/10.1016/j.jmb.2019.12.044.

E. H. Thorarinsdottir, E. Bjornsdottir, B. Benediktsdottir, C. Janson, T. Gislason, T. Aspelund, S.T. Kuna, A.I. Pack, and E.S. Arnardottir, “Definition of excessive daytime sleepiness in the general population: Feeling sleepy relates better to sleep-related symptoms and quality of life than the Epworth Sleepiness Scale score. Results from an epidemiological study,†J Sleep Res., vol. 28(6), e12852, 2019. https://doi.org/10.1111/jsr.12852.

S. M. James, K. A. Honn, S. Gaddameedhi, and H. P. A. Van Dongen, “Shift Work: Disrupted Circadian Rhythms, and Sleep-implications for Health and Well-Being,†Curr Sleep Med Rep., vol. 3(2), pp. 104–112, 2017. https://doi.org/10.1007/s40675-017-0071-6.

P. Afonso, M. Fonseca, and J. F. Pires, “Impact of working hours on sleep and mental health,†Occup Med (Lond.)., vol. 67(5), pp. 377–382, 2017. https://doi.org/10.1093/occmed/kqx054.

J. Ryu, K. Jung-Choi, K.-H. Choi, H.-J. Kwon, C. Kang, and H. Kim, “Associations of shift work and its duration with work-related injury among electronics factory workers in South Korea,†Int. J. Environ. Res. Public Health, vol. 14(1429), 2017. https://doi.org/10.3390/ijerph14111429

M. Majeed, K. Nagabhushanam, S. Arumugam, S. Majeed, and F. Ali, “Bacillus coagulans MTCC 5856 for the management of major depression with irritable bowel syndrome: a randomised, double-blind, placebo controlled, multi-centre, pilot clinical study,†Food Nutr Res., vol. 62, 2018. https://doi.org/10.29219/fnr.v62.1218.

M. Majeed, S. Majeed, K. Nagabhushanam, S. Arumugam, S. Natarajan, K. Beede, and F. Ali, “Galactomannan from Trigonella foenum-graecum L. seed: Prebiotic application and its fermentation by the probiotic Bacillus coagulans strain MTCC 5856,†Food Sci Nutr., vol. 6(3), pp. 666-673, 2018. https://doi.org/10.1002/fsn3.606.

M. Majeed, K. Nagabhushanam, A. Arumugam, S. Natarajan, S. Majeed, K. Beede, and F. Ali, “Cranberry seed fiber: a promising prebiotic fiber and its fermentation by the probiotic Bacillus coagulans MTCC 5856,†Int J Food Sci Technol., vol. 53(7), pp. 1640–1647, https://doi.org/10.1111/ijfs.13747




DOI: http://dx.doi.org/10.18517/ijaseit.11.5.16000

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